Types of folic acid
Folic acid side effects
Folic acid is a water-soluble vitamin, and it is generally not caused within 20 times the adult* requirement. Any excess folic acid is excreted in the urine.
natural folic acid
Natural folic acid is widely found in animal and plant foods, especially in yeast, liver and green leafy vegetables.
synthetic folic acid
There are many foods containing folic acid, but because natural folic acid is extremely unstable and easily oxidized by sunlight and heating, the human body can really obtain not much folic acid from food. The bioavailability of folic acid is low, about 45%. Synthetic folic acid can remain stable for several months or years, is easily absorbed, and has high human availability, which is about twice as high as that of natural products.
Folic acid was originally extracted from * extract and produced by synthetic method. The traditional synthetic route of folic acid takes nitrobenzoic acid as raw material through acyl chloride, condensation, reduction and cyclization. This technological process is long, the yield is low, and the production cost is high. Using tetramethoxypropanol and p-aminobenzoyl-L-glutamic acid as the main raw materials to react with triaminopyrimidine sulfate to produce folic acid, the total yield is 75%, and the purity is 98%.
Physiological function
1) As a coenzyme of the one-carbon unit transferase system in biochemical reactions in vivo, it acts as a one-carbon unit transfer body.
2) Participate in the synthesis of purine and thymine, and further synthesize DNA and RNA.
3) Participate in amino acid metabolism, and act as a one-carbon unit carrier in the interconversion process between glycine and serine, histidine and glutamic acid, and homocysteine and methionine.
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